Spyre Therapeutics, Inc. (SYRE) — Insider Trading Activity

Spyre Therapeutics, Inc. (SYRE) has 120 insider transactions on record, including 0 open-market purchases and 97 sales by company executives and directors. The most recent transaction was filed on 2026-10-01 by Burrows Scott L. The largest single transaction was a sale of $ 399.66M by Harwin Peter Evan.